(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one
(3aS)-2-[(3S)-1-oxidoquinuclidin-1-ium-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
CAS: 813425-83-1
Molecular Formula: C19H24N2O2
(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one - Names and Identifiers
| Name | (3aS)-2-[(3S)-1-oxidoquinuclidin-1-ium-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one |
| Synonyms | LogP Palonosetron N-Oxide Palosetron nitrogen oxides Palonosetron USP Related Compound A PALONOSETRON USP RELATED COMPOUND A (PALONOSETRON N-OXIDE) (S)-3-((S)-1-oxo-3a,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-2(3H)-yl)quinuclidine 1-oxide (3aS)-2-[(3S)-1-oxidoquinuclidin-1-ium-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one (3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one 1H-Benz[de]isoquinolin-1-one,2,3,3a,4,5,6-hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-,(3aS)- |
| CAS | 813425-83-1 |
| InChI | InChI=1/C19H24N2O2/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-20(19)17-12-21(23)9-7-13(17)8-10-21/h2,4,6,13,15,17H,1,3,5,7-12H2/t13?,15-,17-,21?/m1/s1 |
(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one - Physico-chemical Properties
| Molecular Formula | C19H24N2O2 |
| Molar Mass | 312.41 |
| Melting Point | 62 - 65°C |
| Solubility | Dichloromethane (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Light Yellow to Beige |
| pKa | 4.72±0.40(Predicted) |
| Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one - Risk and Safety
| HS Code | 29339900 |
(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one - Introduction
(3aS)-[(3S)-2-]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is an organic compound with the chemical formula C19H19N2O2. The following is an introduction to some of its properties, uses, methods and safety information:
Properties:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a solid with a white to light yellow color. It is an organic cationic compound with a structure similar to a quaternary ammonium salt. Its melting point is 160-165 degrees Celsius.
usage:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a drug intermediate, commonly used in the synthesis of drugs and other organic compounds. It has a wide range of applications in the pharmaceutical field, such as as sedatives, antiepileptic drugs and antidepressants.
preparation method:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is prepared by various methods, and the common method is obtained by reacting palonosetron with an oxidizing agent. The specific method will involve a series of chemical steps and the formation of intermediates, which need to be carried out under suitable experimental conditions.
safety information: because (3aS)-2-[(3S)-]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is an organic compound, it is necessary to pay attention to safety and comply with corresponding laboratory safety rules and regulations when using and handling. It can be irritating and toxic to humans, so direct contact with skin, eyes and inhalation of its dust or vapours should be avoided. Wear protective glasses, gloves and protective masks during operation. In addition, the proper storage and disposal of waste is also very important.
Properties:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a solid with a white to light yellow color. It is an organic cationic compound with a structure similar to a quaternary ammonium salt. Its melting point is 160-165 degrees Celsius.
usage:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is a drug intermediate, commonly used in the synthesis of drugs and other organic compounds. It has a wide range of applications in the pharmaceutical field, such as as sedatives, antiepileptic drugs and antidepressants.
preparation method:(3aS)-2-[(3S)-Ti]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is prepared by various methods, and the common method is obtained by reacting palonosetron with an oxidizing agent. The specific method will involve a series of chemical steps and the formation of intermediates, which need to be carried out under suitable experimental conditions.
safety information: because (3aS)-2-[(3S)-]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one is an organic compound, it is necessary to pay attention to safety and comply with corresponding laboratory safety rules and regulations when using and handling. It can be irritating and toxic to humans, so direct contact with skin, eyes and inhalation of its dust or vapours should be avoided. Wear protective glasses, gloves and protective masks during operation. In addition, the proper storage and disposal of waste is also very important.
Last Update：2024-04-09 20:52:54
![(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one](http://res.chembk.com/assets/images/structure/813425-83-1.gif)
Supplier List
Spot supply
Product Name: Palonosetron Impurity 8 (Palonosetron N-Oxide) (Palonosetron USP Related Compound A) Visit Supplier Webpage Request for quotationCAS: 813425-83-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Palonosetron Impurity 8 (Palonosetron N-Oxide) (Palonosetron USP Related Compound A) Visit Supplier Webpage Request for quotationCAS: 813425-83-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
View History
(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one
茴香霉素(链霉菌素)
n-Octyl triphenylphosphonium bromide
茴香霉素(链霉菌素)
n-Octyl triphenylphosphonium bromide